Moore got emotional and trailed off during her 2025 SAG Awards acceptance speech for her performance in "The Substance."

During her acceptance speech on Sunday, the star expressed her gratitude to have been able to "sometimes succeed and sometimes fail" over the years.

Demi Moore continued her strong awards season run for “The Substance” by taking home the SAG Award for outstanding performance by a female actor in a lead role. The victory was Moore’s third among the major Oscar precursor ceremonies.

Demi Moore called her her fellow actors "my greatest teachers" after she won the 2025 SAG Award for outstanding performance by a female actor in a leading role for her performance in 'The Substance' on Sunday,

Demi Moore celebrated her first-ever SAG Award for Best Actress on Sunday, February 23, after more than 40 years making movies

“Conclave” took home the top film prize, while Demi Moore and Timothée Chalamet won top individual honors. One week before the Academy Awards, the Screen Actors Guild Awards honored the best performances in film and TV, as voted on by the members of SAG-AFTRA. Here is the complete list of SAG winners.