In this article, the authors demonstrate that a normal-phase chromatographic method was stability-indicating for a water-sensitive prodrug. The stress conditions using aqueous and non-aqueous ...

Solid-phase extraction has several advantages over liquid/liquid extraction for extractables and leachables studies. An extractable/leachable (E/L) study is routinely performed on the materials ...

Chromatography of charged analytes is often challenging as they are not retained effectively on the commonly used reversed phase columns and elute in the dead volume. On columns with polar or aqueous ...

This course is suitable for analysts looking to explore different chromatographic techniques/modes applicable for the analysis of polar molecules. It will introduce you to a number of possible ...

When the components in the mixture of solutions are moved forward in the mobile phase by the material moving the sample, these components pass through the stationary phase. The difference in size and ...

High performance liquid chromatography (HPLC) has become an essential technique in pharmaceutical analysis for the separation, identification, and quantification of pharmaceuticals. Due to its high ...