Autophagy (“self-eating”) is the process through which parts of the cell are degraded in the lysosome. Elucidation of the key genes essential for autophagy — originally identified in yeast — has led ...

A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...

Autophagy has been shown to be a key player in preventing aging and diseases of aging, including cancer, cardiovascular disease, diabetes, and neurodegeneration. Notably, research has shown that ...

Autophagy is the major intracellular degradation route in mammalian cells. Systemic ablation of core autophagy-related (ATG) genes in mice leads to embryonic or perinatal lethality, and conditional ...

Autophagy is a critical cellular process that removes damaged organelles and recycles nutrients to maintain homeostasis. In cancer, autophagy plays a complex role, supporting tumor suppression and ...

A new study sheds light on how autophagy, the body’s process for removing damaged cell parts, when impaired, can play a role in causing heart failure. The research team led by Dr. E. Dale Abel, chair ...

TJS and JB are listed as inventors on a related patent, PCT/AU2020/050908 for measurement of autophagy in humans. “The anti-aging MIRACLE.” “Strengthen your immune system.” “Lose weight fast.” These ...

Obesity is a growing global health problem and its prevalence has tripled since 1975. More than 650 million people are affected by this condition worldwide, and 28% of people in Spain over 18 years of ...

Dysfunctional autophagy plays a crucial role in generating epidermal barrier defects that sustain chronic inflammation in AD. hBD-3 could be an autophagy activator and a new approach to the treatment ...

When autophagy faltered in these pre cancer cells, unwanted protein molecules began to build up and stick together. The ...