A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to ...

Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest ...

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

As single-cell genomics experiments grow in size, so too does the need for sequencing. Several large projects have recently called on the relative newcomer to the NGS scene, Ultima Genomics, for their ...

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...