Bottom line: A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease. While the researchers identified the ...

Bottom Line: A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease. While the researchers identified the ...

Mutations in a gene associated with Crohn's disease have been found to rob critical immune cells of their ability to switch ...

Differences in the immune microenvironment between early and late-onset colon and rectal cancer. Feasibility and clinical impact of routine molecular testing of gastrointestinal (GI) cancers at a ...

Analysis of stage of melanoma diagnosis in relation to insurance type and income as indicator of early/late diagnosis. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This ...

NOTCH1 mutations defined a subgroup of patients with adenoid cystic carcinomas who harbored an aggressive disease phenotype, demonstrated a distinct pattern of metastatic spread, and who may be ...

Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes. These mutations are found in nearly 100 per ...

UT Southwestern Medical Center at Dallas researchers have taken the first step in defining the sites in human genes most prone to mutation, which eventually could lead to discovery of the genetic ...

MicroRNAs modulate tumorigenesis through suppression of specific genes. As many tumour types rely on overlapping oncogenic pathways, a core set of microRNAs may exist, which consistently drives or ...

A nonsense mutation is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product. DNA is a chain of many smaller molecules called nucleotides. During protein formation ...

Over a year into the coronavirus pandemic, fears no longer only surround the spread of the virus but also its new forms, or variants. These include B.1.1.7. from the U.K., which was detected in ...

The researchers have clarified that the species with the larger number of changes bear fewer offspring and in that way are removed quite quickly from the population. The results of the study have been ...