A new technique for evaluating drug safety can detect stress on cells at earlier stages than conventional methods, which mostly rely on detecting cell death. The new method uses a fluorescent sensor ...

ToxPredictor accurately predicts drug induced liver injury (DILI) to offer a valuable “go/no-go” tool in clinical decision making.

Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept ...

Chemotherapy appears to activate a stress-sensing system inside immune cells. According to new research from Weill Cornell Medicine and Wake Forest ...

More than a month after the FDA granted its first approval for an amyotrophic lateral sclerosis (ALS) drug in five years, several promising ALS candidates are winnowing their way through clinical ...

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes ...

A newly developed tool, called the DILI-Inpt prognostic score, can predict patients with drug-induced liver injury who are ...