Yusuf Roohani, PhD, machine learning group lead at the Arc Institute, is among a team of researchers training artificial intelligence (AI) models with transcriptome data to predict how cell gene ...

Early detection of safety liabilities of new therapies is a critical biopharmaceutical challenge. Addressing this challenge could significantly advance drug discovery. Advanced human cell models, ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

The authors emphasize regular genomic integrity assessments to ensure models remain representative of patient genetics. Additionally, selecting appropriate cell types proves crucial yet complex, ...

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair ...