Vancomycin has been associated with nephrotoxicity since first becoming available for clinical use. Until recently, the risk for vancomycin-induced nephrotoxicity was presumed to be minimal -- modern ...

Prevention of nephrotoxicity is clearly preferable to treatment, especially given the long life expectancy of survivors of childhood malignancy. General measures to reduce renal damage often include ...

TORONTO—Clinicians can take steps to prevent nephrotoxicity from chemotherapy agents, according to a researcher who spoke here at the Prevention in Renal Disease 8 th Annual Conference. Cisplatin is ...

Drug-induced nephrotoxicity is one of the primary causes of drug failure, as predictions of kidney toxicity during new drug development are still inaccurate. Early detection is critical for reducing ...

Childhood, adolescent, and young adult (CAYA) survivors of cancer are at risk of nephrotoxicity. Surveillance guidelines are important for timely diagnosis and treatment of these survivors, which ...

This study was a phase II, randomized, placebo-controlled design. All patients with solid cancers who were treated with cisplatin (n = 48) were randomly assigned to receive either placebo (n = 25) or ...

Drug-induced kidney injury, or nephrotoxicity, is a common complication in clinical medicine that happens when drugs damage the kidneys. Nephrotoxicity can occur with anti-inflammatory, antibacterial, ...

Oxidative stress could be a key process in acyclovir (ACV)-induced nephrotoxicity. N-acetylcysteine (NAC) is a water-soluble antioxidant with anti-inflammatory activity. This study aimed to evaluate ...

(a) Control; (b, c) Treatment with ACV (150 mg/kg); (d, e, f) Supplementation with NAC (25 mg/kg), NAC (50 mg/kg), and NAC (100 mg/kg), respectively. R, normal renal tubule; N, tubular necrosis; G, ...

Source: Shutterstock Researchers compared the nephrotoxicity of VEGF tyrosine kinase inhibitor (TKI) therapy alone, the combination of a VEGF TKI and an immune checkpoint inhibitor (ICI), and ICI-ICI ...