Purpose: The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of pregabalin are reviewed. Summary: Pregabalin is the first drug to receive approved ...

Pregabalin 82.5mg, 165mg, 330mg; ext-rel tabs. Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.

Maree Smith currently holds competitive research grant funding from the Australian Research Council in collaboration with Boehringer Ingelheim GmbH, from the National Health and Medical Research ...

Although pregabalin is mechanistically similar to gabapentin and shares similar advantages, such as a lack of pharmacokinetic interactions with other medications or enzyme induction, there are several ...