Univeristy of Nebraska-Lincoln (UNL) scientist Ana Maria Vélez is pioneering a genetic treatment to contain western corn rootworm. The research seeks to contain agricultural pests by targeting ...
This week's round-up of pharma licensing deals features alliances involving Tenaya Therapeutics, Sino Bio, Antengene, and A2A ...
Phase 1/2 RESTORE-MASH trial will evaluate safety, pharmacokinetics, and pharmacodynamics of TGM-312 in healthy volunteers and MASH ...
In barely a decade, RNA-mediated interference (RNAi) has evolved from a fascinating biological phenomenon into a powerful experimental tool. Progress in genome sequencing and annotation, as well as ...
RNAi is a powerful tool to used to define cellular mechanisms, and analyze the gene functions of various organisms in laboratories worldwide. Credit: petarg/ Shutterstock.com Fragments of RNA ...
The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...
When it was discovered over a decade ago, RNAi seemed poised to revolutionize medicine. By working to silence defective genes, it has the potential to treat innumerable diseases. Has it delivered? In ...
What does Mello’s prize-winning discovery do? RNAi has garnered more than its fair share of attention lately. Being the subject of a Nobel Prize will do that. But it has also left many in the area ...
Johnson & Johnson has presented clinical trial data linking short-term treatment with RNAi therapy JNJ-3989 to sustained reductions in markers of hepatitis B infection. The data drop comes as J&J runs ...
Farmers looking to gain the upper hand over corn rootworm (CRW) pests have new tools to deploy in the field, thanks to Ribonucleic acid interference (RNAi) technology. RNAi works in CRW as it feeds on ...
As a means of perturbing gene expression—and avoiding manipulation of the genome—RNA interference (RNAi) has distinct advantages. RNAi, it must be said, is hardly unique in its ability to target ...