Medically reviewed by Mary Choy, PharmD Key Takeaways Spironolactone helps treat heart failure by making it easier for the heart to pump blood.The medication lowers high blood pressure by removing ...

Our findings indicate that spironolactone-related hyperkalemia is a much greater problem in everyday practice than in the setting of a clinical trial. "There's no reason to believe that the same ...

Spironolactone is used off-label to slow down and prevent female pattern hair loss. It’s available in both topical and oral formats. Spironolactone works by blocking the hormones that cause certain ...

Please provide your email address to receive an email when new articles are posted on . A potassium binder enabled more patients with heart failure to stay on ...

An oral potassium binder taken daily can enable the safe use of mineralocorticoid receptor antagonists (MRAs) in patients with heart failure with reduced ejection fraction (HFrEF) who are at risk for ...

CHICAGO -- A mineralocorticoid receptor antagonist (MRA) was unable to further improve 3-year outcomes of acute myocardial infarction (MI) in the modern era, based on the CLEAR OASIS 9 trial. Among ...

The routine administration of spironolactone to patients after a myocardial infarction (MI) did not reduce either of the coprimary outcomes in the CLEAR SYNERGY (OASIS 9) trial. However, there was a ...

Spironolactone showed no significant benefit in reducing the composite of cardiovascular mortality and heart failure ...