THREE zymogens of proteolytic enzyme in pancreas (two chymotrypsinogens and trypsinogen) are known at present. In this communication, we report the occurrence of another inactive precursor of ...

† Most-abundant zymogen granule proteins. ‡ Different isoforms present in zymogen granules. § Validated by morphological studies after identification by mass spectrometry. As the molecular mechanisms ...

Proplasmepsin II is the zymogen of plasmepsin II, an aspartic proteinase used by Plasmodium falciparum to digest hemoglobin during the blood stage of malaria. A large shift between the N–domain and ...

Scientists have identified a protein that is necessary for secretion of digestive enzymes by the pancreas. The research, published in the September issue of Developmental Cell, enhances the ...