You have full access to this article via your institution. The Supplementary Information online provided with the paper provides the mass spectrometry data for identifying the APP isoform—rat membrane ...

Two years later, Japanese electron microscopist Eichi Yamada coined the term “caveolae,” from the Latin for “little caves,” to describe these invaginations. Caveolae have since turned up in several ...

Although caveolae are well-characterized subdomains of glycolipid rafts, their distinctive morphology and association with caveolins has led to their internalization being considered different from ...

The surface of fat cells contains many small pockets called caveolae (because they look like caves in an electron microscope). Although their role is not clear, Paul F. Pilch and colleagues review ...

Lipid membrane curvature plays important roles in various physiological phenomena. Curvature-regulated dynamic membrane remodeling is achieved by the interaction between lipids and proteins. So far, ...

Microbiologists at Duke University Medical Center show from a review of studies that a puzzling depression in cells may serve as an invading pathway for pathogens such as the AIDS virus HIV and other ...

Researchers at CNIC uncovered a vital role for caveolae in fat cell expansion. These membrane structures shield adipocytes from mechanical stress, enabling safe energy storage and preventing ...

A scientist at Leeds whose research is challenging conventional thinking on how the cholesterol-reducing drugs statins benefit cardiac patients, has secured funding to further investigate her findings ...

A study carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) heralds a paradigm change in the field of mechanobiology. The study reveals that cells respond to forces of ...

During obesity, we observed that the number of caveolae and their detachment from the membrane get out of sync." Dr. Claudia Matthaeus, Max Delbrueck Center for Molecular Medicine In November, ...