The final cytokinesis event involves severing of the connecting intercellular bridge (ICB) between daughter cells. FIP3-positive recycling endosomes (FIP3 endosomes) and ESCRT complexes have been ...
The general amino acids permease Gap1p provides yeast with sufficient amino acids to maintain protein synthesis. Gap1p is translocated to the plasma membrane when amino acids become limiting, a ...
This is a preview. Log in through your library . Abstract We have investigated two aspects of membrane traffic at early stages of endocytosis: membrane fusion and microtubule-dependent transport. As a ...
This is a preview. Log in through your library . Abstract We investigated intracellular trafficking of GM1 ganglioside in Niemann-Pick C1 (NPC1)-deficient Chinese hamster ovary cells [NPC1(-) cells] ...
In a paper that will be published online in advance of its July 1st publication date, Drs. Niko Geldner, Joanne Chory and colleagues (The Salk Institute and HHMI) demonstrate that endosomes can ...
Does jammed-up protein recycling in neurons cause proteins to spill into the cerebrospinal fluid in Alzheimer’s disease? As reported in the November 25 Science Translational Medicine, scientists led ...
Rather than tackle a criminal in your bedroom, why not prevent him from entering your home? That’s the therapeutic takeaway from a new study on intracellular trafficking of amyloid-β precursor protein ...
Despite its isolation three decades ago, Ebola virus continues to cause periodic outbreaks of severe hemorrhagic fever in humans, and the closely related Marburg virus is responsible for a recent ...
In a groundbreaking leap forward for cancer therapy, scientists in Japan have created a tiny delivery system that helps ...
The latest short science news items from C&EN. A complicated sequence of events follows once an RNA drug is injected into the body. After the lipid-packaged RNA arrives at a cell, it pushes through ...
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