A newly discovered biological chain reaction explains how high levels of a common brain chemical can lead to cellular ...

A hidden molecular chain reaction in the brain may push key cellular systems into overdrive in autism—and scientists just found a way to switch it off.

A new study discovers how nitric oxide triggers a biochemical domino effect in the brain, leading to mTOR overactivation in ...

Think of the brain as a city with traffic lights that keep signals flowing smoothly. In a new study, researchers followed a clue about nitric oxide, a common chemical messenger, and found that, in ...

Learning more about the mTOR complex and how it works is a stepping stone for others who might look for cancer therapies or ways to help treat diabetes and other diseases. In the world of biology, ...

Individuals with certain comorbidities, such as obesity and diabetes, are at a higher risk of being severely infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal ...

Fig 1. PI3K/AKT/mTOR signaling pathway showing interacting activation and regulatory feedback loops. Adapted from Hoeffer and Klann. 35 Mammalian target of rapamycin (mTOR) is a serine-threonine ...