Cryo-electron tomography (cryo-ET) can provide invaluable insights into subcellular structures in their native environment at molecular resolution. Cryo-focused ion beam (cryo-FIB) has been widely ...
The researchers demonstrated the utility of their technique on a slice of a mouse brain, 200 microns (0.2 millimeters) in thickness. First, they made their tissue sample see-through using a tweaked ...
Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...