136 Real-world evidence comparing the vitamin-K-antagonist phenprocoumon versus direct oral anticoagulants in patients with atrial fibrillation in Germany ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process ...

To practice high quality healthcare, clinicians must be able to diagnose correctly, provide preventative and treatment interventions based on the best available evidence, and ensure decisions are ...

Objectives Alteplase is commonly recommended for acute ischaemic stroke within 4.5 hours after stroke onset. The Third European Cooperative Acute Stroke Study (ECASS III) is the only trial reporting ...

Introduction In 2013, the Observing Patient Involvement in Decision Making instrument (OPTION-5) was developed to measure levels of shared decision-making (SDM) in consultations.1 Since then, it has ...

Objectives The anti-Mullerian Hormone (AMH) test is a blood test indicating ovarian reserve (i.e. the number of eggs left in a woman’s ovaries). The test is helpful in assisted reproduction (indicates ...

Objectives Incidental pancreatic cystic lesion (PCL) prevalence is approximately 10%. PCL surveillance is required because a small subset have malignant potential. While several surveillance ...

The incorporation of publications that have been retracted is a risk in reliable evidence synthesis. Retraction is an important mechanism for correcting the literature and protecting its integrity.

56 Evaluating the choosing wisely questions: a pilot study of methods to engage consumers in health decisions across health literacy levels ...

Evidence-based medicine integrates clinical experience with patients' values and the best available evidence.1 In the past, clinicians took responsibility not only for being well informed about the ...

New government legislation is necessary to ensure full transparency of industry payments in the UK’s healthcare. A first step should involve challenging the industry-driven discourse that allows ...

Objectives To develop a core outcome set (COS) for oropharyngeal dysphagia (swallowing disorder) interventions in Parkinson’s disease by agreeing core outcomes and definitions, outcome measurement ...