The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case o ...

A rare T-cell lymphoma after chimeric antigen receptor (CAR) T-cell therapy for myeloma was linked to CCR4 overexpression and vector integration, which highlights the need for monitoring after CAR ...

Dry eye is a common, painful ocular disturbance that can result from systemic inflammatory diseases, localized eye problems, or commonly used medications. Current treatments address symptoms, but a ...

A small-molecule drug proves its mettle in the treatment of spinal muscular atrophy, a disease amenable to intervention at the pre-mRNA level.

The benefits of women’s health research haven’t been limited to women. But actions by the Trump administration threaten to dismantle the hard-won progress in this area.

Current international clinical practice guidelines recommend complete revascularization for patients with ST-segment elevation myocardial infarction (STEMI) with multivessel coronary artery disease ...

In 1979, China implemented the one-child family policy, which restricts many couples to a single offspring. The authors describe the policy's success in slowing population growth as well as its adv ...

Respiratory distress developed in a neonate after delivery at 32 weeks of gestation. Endotracheal intubation was unsuccessful, and he died 4 hours after delivery. A postmortem esophagram obtained a ...

To the Editor: In their article on the PROPEL2 trial, Savarirayan and colleagues (Feb. 27 issue)1 describe the results of a phase 2 dose-finding trial of infigratinib in children with achondroplasi ...

To the Editor: Cederholm and Bosaeus (July 11 issue)1 propose three causal subtypes of malnutrition: disease-related with and without underlying inflammation and “starvation due to inadequate ...

An 83-year-old man presented with fatigue, weight loss, and postural hypotension. Computed tomography of the abdomen revealed marked enlargement of both adrenal glands, and a diagnosis of primary a ...