BMJ

Oral sildenafil for the treatment of Raynaud’s phenomenon and digital ulcers secondary to systemic sclerosis

Medical University of South Carolina, Division of Rheumatology, Charleston, South Carolina, USA Correspondence to: Dr J Gore Medical University of South Carolina, Division of Rheumatology, 96 Jonathon ...
BMJ

Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke

2 Department of Medicine, Rheumatology Unit, Karolinska Institutet/Karolinska Hospital, Stockholm, Sweden 3 Unit of Clinical Immunology, Uppsala University/Akademiska Sjukhuset, Uppsala, Sweden 4 ...
BMJ

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

1 Università degli Studi di Genova and Istituto Giannina Gaslini, Genoa, Italy 2 Istituto Giannina Gaslini, Genoa, Italy ...
BMJ

Validation of EULAR primary Sjögren's syndrome disease activity (ESSDAI) and patient indexes (ESSPRI)

1 Center of Clinical Epidemiology, Hôpital Hotel Dieu; INSERM U738, Université Paris-René Descartes, Paris, France Objectives To validate the two recently developed disease activity indexes for ...
BMJ

Common mental disorders within chronic inflammatory disorders: a primary care database prospective investigation

Objective There is inconsistent evidence about the association between inflammatory disorders and depression and anxiety onset in a primary care context. The study aimed to evaluate the risk of ...
BMJ

Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 years

2 Department of Health Sciences Research, Mayo Clinic and Mayo Graduate School of Medicine, Rochester, Minnesota, USA 3 Division of Rheumatology, Mayo Clinic and Mayo Graduate School of Medicine, ...
BMJ

Long-term follow-up on effectiveness and safety of etanercept in juvenile idiopathic arthritis: the Dutch national register

Department of Paediatrics/Paediatric Rheumatology, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands Department of Paediatrics/Paediatric ...
BMJ

The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 ...

Background: MMP-13 is one of the most important metalloproteases (MMP) involved in osteoarthritis. Licofelone, a novel dual inhibitor of cyclo-oxygenases (COX) and 5-lipoxygenase (5-LOX), can modulate ...
BMJ

Survival in adults and children with systemic lupus erythematosus: a systematic review and Bayesian meta-analysis of studies from 1950 to 2016

Objective To determine trends in survival among adult and paediatric patients with systemic lupus erythematosus (SLE) from 1950 to the present. Methods We performed a systematic literature review to ...
BMJ

Prediction of progression of interstitial lung disease in patients with systemic sclerosis: the SPAR model

Objectives To identify the predictive clinical characteristics and establish a prediction model for the progression of mild interstitial lung disease (ILD) in patients with systemic sclerosis (SSc).
BMJ

Predictors of patient relevant outcome after total hip replacement for osteoarthritis: a prospective study

Department of Orthopaedics, Lund University Hospital, Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden Correspondence to: Dr A-K Nilsdotter, Department of Orthopaedics, Lund University ...
BMJ

Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide

Introduction: Potential hepatotoxicity associated with disease-modifying antirheumatic drugs (DMARDs) requires laboratory monitoring. In patients with rheumatoid arthritis (RA) or psoriatic arthritis ...