136 Real-world evidence comparing the vitamin-K-antagonist phenprocoumon versus direct oral anticoagulants in patients with atrial fibrillation in Germany ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process ...

To practice high quality healthcare, clinicians must be able to diagnose correctly, provide preventative and treatment interventions based on the best available evidence, and ensure decisions are ...

Objectives Alteplase is commonly recommended for acute ischaemic stroke within 4.5 hours after stroke onset. The Third European Cooperative Acute Stroke Study (ECASS III) is the only trial reporting ...

Objectives The anti-Mullerian Hormone (AMH) test is a blood test indicating ovarian reserve (i.e. the number of eggs left in a woman’s ovaries). The test is helpful in assisted reproduction (indicates ...

Objectives Incidental pancreatic cystic lesion (PCL) prevalence is approximately 10%. PCL surveillance is required because a small subset have malignant potential. While several surveillance ...

The incorporation of publications that have been retracted is a risk in reliable evidence synthesis. Retraction is an important mechanism for correcting the literature and protecting its integrity.

56 Evaluating the choosing wisely questions: a pilot study of methods to engage consumers in health decisions across health literacy levels ...

Evidence-based medicine integrates clinical experience with patients' values and the best available evidence.1 In the past, clinicians took responsibility not only for being well informed about the ...

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia. Design Our study design was a ...

Objectives Endometrial cancer (EC) incidence has been rising globally, while mortality has remained stable, particularly in Nordic countries. This study aimed to explore the role of transvaginal ...

The introduction of generative large language models (LLMs) has led to the exploration of their use in evidence synthesis tasks, such as literature searches,1 screening,2 3 risk of bias assessment,4 5 ...