Discovery of potential degraders (BacPROTACS) for essential tRNA synthetases in Mycobacterium tuberculosis. This repository is work in progress. In this project, the main objective is to prioritise a ...

Here’s what you’ll learn when you read this story: Mycobacterium tuberculosis, which causes the potentially fatal respiratory infection of the same name, was found to use a system known as PrrAB to ...

A newly approved diagnostic test could give UK clinicians a more accurate way to identify latent and active tuberculosis (TB). The Medicines and Healthcare products Regulatory Agency (MHRA) has ...

Painstaking experiments have revealed the cellular signatures that signify a tuberculosis infection, providing a series of targets for new vaccines that could finally subdue one of the world’s leading ...

Across Europe, tuberculosis (TB) is once again raising alarm, particularly the extensively drug-resistant form (XDR-TB), which is proving as deadly as before antibiotics were discovered. A large ...

Yolo County officials traced contacts after a TB case surfaced at Cache Creek Casino. California saw 2,100 TB cases in 2024, with a rising mortality rate of 14%. Health agencies stress screening and ...

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia However, based on genetic code redundancy and inability to obtain particular amino acid substitutions with single ...

When the antibiotic bedaquiline was introduced in 2012, it was the first new tuberculosis drug in over 40 years. Bedaquiline quickly became the key drug in all standard drug-resistant tuberculosis ...

Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...

Tuberculosis (TB) remains one of humanity’s oldest and most persistent health challenges. Despite significant medical advances, this infectious disease continues to affect millions globally, with ...

It's unclear if the patient is a student, faculty member or staff member. A case of active tuberculosis has been confirmed at a Florida high school, according to state health officials. The Florida ...