"Oh my goodness, it has been quite a ride. Thanks, everybody," he said, surrounded by his wife of 42 years, Carol Hagen, and his colleagues after a highlights montage aired.

Friday will make the end of an era for NBC News and Lester Holt.

“As an anchor, it’s been an honor to lead this program, and an honor to be welcomed into your homes. I’m so grateful for your trust.”