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Dr. Xanthine on Instagram: "video source RCSB protein source data bank via pdb-101, review by englander and mayne in 2021 published in pnas "Proteins must fold to their active native state when they emerge from the ribosome and when they repeatedly unfold and refold during their lifetime (1, 2). Early in the history of the folding field, experimentalists simply assumed that proteins fold through distinct intermediate states in a distinct pathway (Fig. 1A), as seen for a classical biochemical pat
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Dr. Xanthine on Instagram: "video source RCSB protein source data bank via pdb-101, review by englander and mayne in 2021 published in pnas "Proteins must fold to their active native state when they emerge from the ribosome and when they repeatedly unfold and refold during their lifetime (1, 2). Early in the history of the folding field, experimentalists simply assumed that proteins fold through distinct intermediate states in a distinct pathway (Fig. 1A), as seen for a classical biochemical pat
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Dr. Xanthine on Instagram: "drew urasil and inosine on a cookie because i always think of U and I. video source RCSB protein source data bank via pdb-101, caption from libretexts "First, a quick review of some key thermodynamics terms. Recall that the standard Gibbs free-energy change of a reaction (螖Go) is the difference in energy between reactants and products at standard conditions. Gibbs free-energy change is a combination of enthalpy change (螖Ho) and entropy change (螖So): 螖G=螖Ho鈭扵螖So where
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