How to Remember Side Effects of Valproate/ Valproic Acid in 4 Minutes??
3:53
YouTubePharmacology Made Simple By Dr. Yogesh Gulati
How to Remember Side Effects of Valproate/ Valproic Acid in 4 Minutes??
Simple and short presentation of the side effects of Valproate/Valproic acid. COMING SOON: Complete Course on Classification of Drugs The content in the video is for the purpose of information and education ONLY and is NOT intended to replace or is NOT a substitute for professional medical diagnosis, treatment, or physician advise. The ...
50.9K viewsJul 8, 2018
Valproate Mechanism of Action
Epilepsy (Generalized Tonic–Clonic Seizures) – Drug of Choice Tab. Sodium Valproate 500 mg PO BD Dose: Start 10–15 mg/kg/day, increase to 20–30 mg/kg/day in divided doses. Uses First-line drug for generalized tonic–clonic seizures. Also useful in myoclonic and absence seizures. Mechanism of Action ↑ GABA levels → enhances inhibitory transmission. Blocks voltage-gated sodium channels → stabilizes neuronal membranes. Blocks T-type calcium channels → suppresses abnormal discharges. Prescription Tab
0:25
Epilepsy (Generalized Tonic–Clonic Seizures) – Drug of Choice Tab. Sodium Valproate 500 mg PO BD Dose: Start 10–15 mg/kg/day, increase to 20–30 mg/kg/day in divided doses. Uses First-line drug for generalized tonic–clonic seizures. Also useful in myoclonic and absence seizures. Mechanism of Action ↑ GABA levels → enhances inhibitory transmission. Blocks voltage-gated sodium channels → stabilizes neuronal membranes. Blocks T-type calcium channels → suppresses abnormal discharges. Prescription Tab
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UKMLA_Drop on Instagram: "IM getting really sick of YOU!! ✔️ Correct answer: C – Levetiracetam **Answer Breakdown** **A. Sodium valproate – Incorrect** - Common side effects: - Weight gain - Tremor - Hair thinning - Less associated with irritability or aggression **B. Carbamazepine – Incorrect** - Can cause: - Diplopia - Ataxia - Hyponatraemia - Behavioural aggression is not classic **C. Levetiracetam – Correct** - Well-known for behavioural side effects: - Irritability - Agitation - Mood swings
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