What are the benefits and risks of HRT?
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The controversy surrounding Hormone Replacement Therapy (HRT) escalated primarily due to findings from the Women’s Health Initiative (WHI) study, a large-scale research effort launched in the early 2000s. Initially intended to assess the long-term benefits of HRT in postmenopausal women, the WHI unexpectedly reported concerning outcomes related to certain types of hormone therapy. Specifically, the study suggested that a combination of conjugated equine estrogen (Premarin) and medroxyprogesteron
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